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	<title>Sickle Cell Cure Foundation &#187; broylesr</title>
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	<link>http://sicklecellcurefoundation.org</link>
	<description>a nonprofit corporation working to cure sickle cell disease</description>
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		<title>Eradicating a Deadly Disease Through Science, Love and Music.</title>
		<link>http://sicklecellcurefoundation.org/2010/02/eradicating-a-deadly-disease-through-science-love-and-music/</link>
		<comments>http://sicklecellcurefoundation.org/2010/02/eradicating-a-deadly-disease-through-science-love-and-music/#comments</comments>
		<pubDate>Sat, 27 Feb 2010 22:12:13 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Breaking News]]></category>
		<category><![CDATA[funding]]></category>
		<category><![CDATA[Living with SCD]]></category>
		<category><![CDATA[scientific research]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>
		<category><![CDATA[sickle cell disease cure]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.org/?p=904</guid>
		<description><![CDATA[Article by Laura Jenney Of Mindsweep Entertainment &#38; Promotions VPofMindsweep@aol.com Jacksonville, FL 1-20-2010 The arrival of the year 2010 is an exciting time indeed! Not only are we embracing the beginning of a brand new year, but a brand new decade as well. It&#8217;s a time of great possibilities and full of promise. A time [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/Jameel.jpg"><img src="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/Jameel.jpg" alt="" title="Jameel" width="240" height="267" class="alignleft size-full wp-image-906" /></a>Article by Laura Jenney<br />
Of Mindsweep Entertainment &amp; Promotions<br />
VPofMindsweep@aol.com<br />
Jacksonville, FL<br />
1-20-2010</p>
<p>The arrival of the year 2010 is an exciting time indeed! Not only are we embracing the beginning of a brand new year, but a brand new decade as well. It&#8217;s a time of great possibilities and full of promise. A time of new beginnings, as we say goodbye to things of the past while ridding ourselves of the negative effects of old habits, patterns and thinking; and embark upon &#8216;the bold new NOW&#8217;, with great determination to better and/or to reinvent ourselves, to strive to be THE BEST we can be; be THE MOST we can be; progressing forward towards the attainment of our dreams and goals, and striving to arrive at our ultimate state of Zen in 2010. &#8230;In doing so, not only on an individual level, but on a community, national and global level as well, we are in fact, casting the mold of our tomorrows.</p>
<p>We are off to an excellent start, as you can now add to your list of New Year&#8217;s resolutions that while having an absolute blast this year while doing so, YOU can help eradicate a deadly disease off the face of the planet in the process! &#8230;Now I know some of you are probably thinking at this point that &#8220;Ms. Laura has worked with ONE TOO MANY rock stars in 2009,&#8221; but it&#8217;s the truth! (&#8230;About the eradicating a deadly disease thing anyway.) Allow me enlighten you to the details&#8230;</p>
<p>Via the hard work, dedication, and deep compassion of two absolutely brilliant men, Doctor and esteemed Bio Chemist Robert H. Broyles and Musician/Songwriter, Promoter, Talk Show Host, Radio Personality J. R. Perry III, an immense amount of suffering worldwide can be eliminated this year by the eradication of the deadly disease Sickle Cell Anemia for which Dr. Robert H. Broyles HAS THE CURE; and by which J. R. Perry is helping to raise the funding, (and awareness), needed to get this cure to those who need it, (and to hasten the process of doing so), via organizing a series of super dynamic concerts worldwide, featuring renowned and/or legendary acts in every genre imaginable.</p>
<div id="attachment_908" class="wp-caption aligncenter" style="width: 456px"><a href="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/LoveDrop1.jpg"><img class="size-full wp-image-908" title="LoveDrop" src="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/LoveDrop1.jpg" alt="" width="446" height="248" /></a><p class="wp-caption-text">(Dr. Robert H. Broyles left, J. R. Perry right.)</p></div>
<p>Dr. Robert H. Broyles, who is the Founder and President of The Sickle Cell Cure Foundation, and has discovered/developed a cure for the disease via primarily the utilization of Gene Regulation Therapy, and has secured and obtained the US patent for this proven way it would work on April, 14, 2009.</p>
<p>(Though Dr. Robert H. Broyles actually discovered a way in which the cure would work as early as 2006; though getting it into the hands of those who need it is an extremely slow moving and arduous task, largely due to the extreme amount of bureaucratic &#8216;red tape&#8217; involved in the process.)</p>
<p>SCCF&#8217;s patents in Australia, and the European Union, (France, Germany, and Greece), are also already secured and maintained through Dr. Broyles&#8217; outstanding work to not only end this deadly disease, but quite possibly Parkinson&#8217;s Disease and other diseases as well, through Gene Regulation Therapy and Iron Management.</p>
<p>Not only is Doctor Robert H. Broyles an incredibly brilliant scientist, (one of the Principal Investigative Scientists in the field of Gene Regulation Therapy for Sickle Cell Disease, with over thirty-five years of research experience to add to his extraordinarily impressive and numerous credits), Dr. Broyles is an extremely kind man of sincere and deep care and compassion for those he has dedicated his life to heal. &#8216;Doctor Bob,&#8217; (as I have nick named him out of my ultimate respect and admiration for him as both a scientist and as a great individual), shares an example of the many e-mails from people all around the world, which greatly moves Dr. Broyles, and serves as his driving force for doing the amazing and outstanding work that he does. Here is one example of the many e-mails in which Dr. Robert Broyles receives regularly: &#8220;Please, I beg you in the name of the most high-grade God. How do I access the cure? This pain is too much. Please don&#8217;t let me die. Please.&#8221; Needless to say, Dr. Robert H. Broyles is not only a man of exceptional mind, but also a man of exceptional heart and soul as well, for the work he has done and continues to do with great determination and dedication; which in my opinion, is worthy of a Nobel Prize. I would also like to add that out of the many renowned stars that I have worked with over the years as a PR, Press and Media Relations Specialist, (mostly in the music industry, though I have also written for/about a number of high profile, US political figures as well), I have to say that Dr. Robert H. Broyles is indeed THE brightest shining true &#8216;superstar&#8217; I have ever had the pleasure of working with thus far!</p>
<p>Another great man of uncommon valor and brilliance in his own fields of expertise who is working hard to bring this cure, (and expedite the process of doing so), to those in need of it is J. R. Perry III; who is in the process of organizing a series of multi-artist concerts worldwide to both, generate funding and awareness concerning this deadly disease.</p>
<p>Because, (to spite misconceptions), Sickle Cell Anemia is a disease that effects people of ALL races, in all countries, and of all social economic status, renowned Promoter and long time Sickle Cell Disease Activist, J. R. Perry&#8217;s exciting concert tour, (&#8220;The Cure Every Cell Tour&#8221;), will feature a dynamic array of outstanding artists from every genre imaginable to strategically generate as much &#8216;broad audience appeal&#8217; as possible to both educate, (on a very large scale), about this deadly and extremely painful disease, dispel the many misconceptions concerning this disease, and to raise the necessary funding to complete the final stages of clinical trials required, (by the medical regulations in the US), before making this cure available to patients within the US. (Though notably, Dr. Broyles&#8217; procedural cure is currently already available outside of the US in a number of other countries.)</p>
<p>J. R. Perry&#8217;s dedicated involvement as both a Sickle Cell Disease Awareness Activist and his hard work and effort at organizing a massive world tour to combat this disease and bring forth the cure is nothing less of a labor of love. J. R. Perry&#8217;s own ten year old son Jameel suffers from Sickle Cell Disease, and has already endured a stroke, (at age 9), and has to receive regular blood transfusions, suffers chronic pain, as well as has a potentially life threatening compromised immune system because of this disease.</p>
<p><div id="attachment_906" class="wp-caption alignleft" style="width: 250px"><a href="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/Jameel.jpg"><img src="http://sicklecellcurefoundation.org/wp-content/uploads/2010/02/Jameel.jpg" alt="Jameel" title="Jameel" width="240" height="267" class="size-full wp-image-906" /></a><p class="wp-caption-text">Ten year old, Jameel Perry, son of J. R. Perry III.</p></div><br />
Ten year old, Jameel Perry, son of J. R. Perry III.</p>
<p>Though we are at the beginning phases of organizing this historic &#8216;tour for the cure&#8217;, amongst the first outstanding artists to join this effort includes blues, R&amp;B and jazz legend Chick Willis, (www.myspace.com/chickwillis), sizzling Latin/salsa sensations Orquesta Fiesta, (www.myspace.com/clarasalsa), jam&#8217;s absolutely smoking and super fast rising band Bodhi, (www.bodhilive.com), and prolific Vocalist Dan Shafer, (known for his work with a number of renowned bands such as Mercenary, featuring Rusty DAddio of Ronnie James Dio and Richie Blackmore); and well renowned for his work in numerous commercials, and is the Executive Producer of The Rock &amp; Load Show, amongst Dan&#8217;s immense and impressive list of professional credits; (www.myspace.com/danshafer). And most recently, joining in this effort will be world renowned Latin and jazz recording artist Eddie Benitez. (www.myspace.com/eddiebenitez).</p>
<p>More respected artists will be listed in upcoming press releases as they come aboard on this project: as we at Mindsweep Entertainment &amp; Promotions are embarking on a massive PR, press and media, (and cross promotional), campaign to further promote this very important, life saving and history changing tour, (and as a promotions &#8216;perk&#8217; for the artists, sponsors and to everyone associated with this tour, as a token of our sincere and immense amount of appreciation for their involvement and help): and of course, to keep everyone updated on upcoming concert dates, the artists involved, upcoming TV and radio appearances and news concerning this tour. J. R. Perry III incidentally, is also the Owner of Love Drop Radio, where artists involved with this tour will be featured as guests on Love Drop Radio&#8217;s esteemed programming to further promote this noble cause.</p>
<p>Renowned artists that would like to add extra concert dates to their 2010 concert schedule while helping to eradicate this deadly disease in the process by getting involved can do so by contacting me, Laura Jenney at any of the following e-mail addresses: VPofMindsweep@aol.com, Jcongalady@aol.com or laura@tntbooking.com, or by calling 904-378-8357. (The Jcongalady@aol.com e-mail address always gets seen and answered the quickest.)</p>
<p>Concert venues and corporate sponsors that would like to get involved with this phenomenal opportunity and make a huge humanitarian difference via this project and vital cause, please contact J. R. Perry III by e-mail at Lovedropradio@hotmail.com or myself at VPofMindsweep@aol.com. (Sponsorship incentives are absolutely exceptional and unbeatable, I might add!)</p>
<p>For more information about the outstanding work that Dr. Robert H. Broyles and all of those at work at The Sickle Cell Cure Foundation are doing, please visit their web site at http://www.sicklecellcurefoundation.org.</p>
<p>To make a much needed and appreciated donation to help bring forth the cure and to wipe Sickle Cell Disease, (and quite possibly other diseases as well), donations can be made by:</p>
<ul>
<li>Clicking on the gold <strong>Donate button</strong> on the upper right hand side of this webpage, and use a credit card through PayPal; Or&#8230;</li>
<li>Send a check addressed to:<br />
The Sickle Cell Cure Foundation<br />
601 NW 13th Street<br />
Oklahoma City , OK 73103.</li>
</ul>
<p>The Sickle Cell Cure Foundation Inc., or (SCCF), is a nonprofit corporation registered in the State of Oklahoma. It&#8217;s 501(C) (3) status has been approved by the Internal Revenue Service of the United States as of February 12, 2007; and all donations are tax deductible.</p>
<p>And that&#8217;s how YOU TOO can help eradicate the deadly disease Sickle Cell Anemia off the face of the planet while having an absolute blast doing so, simply by attending a concert on the &#8220;The Cure Every Cell Tour&#8221; coming to a concert venue near you very soon! Now isn&#8217;t that an absolutely GREAT resolution to start out a New Year and decade? &#8230;I&#8217;m talking WAAAAY more fun than trying to quit bad habits, dieting and exercise!</p>
<p>The End.</p>
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		<title>National Sickle Cell Month</title>
		<link>http://sicklecellcurefoundation.org/2009/09/national-sickle-cell-month/</link>
		<comments>http://sicklecellcurefoundation.org/2009/09/national-sickle-cell-month/#comments</comments>
		<pubDate>Fri, 04 Sep 2009 23:05:36 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Living with SCD]]></category>
		<category><![CDATA[clinical trials]]></category>
		<category><![CDATA[non-profit]]></category>
		<category><![CDATA[sickle cell cure foundation]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>
		<category><![CDATA[sickle cell disease cure]]></category>
		<category><![CDATA[united states patent]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.org/?p=743</guid>
		<description><![CDATA[The Sickle Cell Cure Foundation, Inc. (SCCF) has made significant progress in recent months, including a U.S. patent issued 14 April 2009, and further laboratory discoveries showing that less DREPAC is needed than previously believed to reverse sickle cell! To keep this progress going, we need your help! It is our goal to have clinical [...]]]></description>
			<content:encoded><![CDATA[<p><strong><img class="alignleft" title="sickle-cells-300x300" src="/wp-content/uploads/2009/09/sickle-cells-300x300.jpg" alt="" width="300" height="300" />The Sickle Cell Cure Foundation, Inc. (SCCF)</strong> has made significant progress in recent months, including a <strong>U.S. patent issued 14 April 2009</strong>, and further laboratory discoveries showing that less <strong>DREPAC</strong> is needed than previously believed to reverse sickle cell! To keep this progress going, we need <strong>your help!</strong> It is our goal to have <strong>clinical trials</strong> underway by this time next year! Please click the <strong>donate button and give generously this month</strong> – National Sickle Cell Month.  SCCF is a 501(c)(3) non-profit research foundation and <strong>all donations</strong> are 100% tax deductible.</p>
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		<item>
		<title>About sickle cell disease&#8230;</title>
		<link>http://sicklecellcurefoundation.org/2009/08/about-sickle-cell-disease/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/about-sickle-cell-disease/#comments</comments>
		<pubDate>Sun, 16 Aug 2009 03:42:52 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Our Research]]></category>
		<category><![CDATA[scientific research]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=442</guid>
		<description><![CDATA[&#8220;Everything we know about genes we learned first about the beta globin gene. Everything we know about molecular disease we first learned about sickle cell disease&#8221; Francis Collins, NIH, former Director of the Human Genome Project]]></description>
			<content:encoded><![CDATA[<p><img class="alignleft" title="Genes" src="/wp-content/uploads/2009/08/genes-75x75.jpg" alt="" width="75" height="75" />&#8220;Everything we know about genes we learned first about the beta globin gene.  Everything we know about molecular disease we first learned about sickle cell disease&#8221;<br />
Francis Collins, NIH, former Director of the Human Genome Project</p>
]]></content:encoded>
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		<title>A cure for sickle cell disease from our own bodies&#8230;</title>
		<link>http://sicklecellcurefoundation.org/2009/08/a-cure-for-sickle-cell-disease-from-our-own-bodies/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/a-cure-for-sickle-cell-disease-from-our-own-bodies/#comments</comments>
		<pubDate>Sun, 09 Aug 2009 05:13:25 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Our Research]]></category>
		<category><![CDATA[sickle cell]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>
		<category><![CDATA[sickle cell disease cure]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=241</guid>
		<description><![CDATA[We are very proud to announce major progress in the search for a cure for sickle cell disease (SCD), the first genetic disease to be understood and a major disease that kills an estimated half-million people world-wide each year. As high as one in every four black persons in certain parts of Africa carries the [...]]]></description>
			<content:encoded><![CDATA[<p><img class="alignleft" title="Vitruvian-Man" src="/wp-content/uploads/2009/08/Vitruvian-Man.jpg" alt="" width="300" height="425" />We are very proud to announce major progress in the search for a cure for sickle cell disease (SCD), the first genetic disease to be understood and a major disease that kills an estimated half-million people world-wide each year.  As high as one in every four black persons in certain parts of Africa carries the sickle cell gene.  In the United States the incidence is 1 in 12 for African Americans, and approximately 78,000 have SCD.  Dr. Robert H. Broyles, a medical school professor and researcher in Oklahoma City, has discovered a protein that is grown in our own bodies that will silence the sickle cell gene and activate a normal gene in its place.  Unlike current treatments that are only partially effective or treat the damage caused by SCD, this cure is very specific for the cause, easy to deliver, and beneficial to the whole body.  We are working to get this treatment through safety trials and into the clinics where it will be available to all who have sickle cell disease.  Our vision is a global one: our goal is to get this cure to each of the millions of people world-wide who have SCD and/or Beta-Thalassemia.</p>
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		<slash:comments>150</slash:comments>
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		<item>
		<title>Alicia and Dominick Bibbs</title>
		<link>http://sicklecellcurefoundation.org/2009/08/alicia-and-dominick-bibbs/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/alicia-and-dominick-bibbs/#comments</comments>
		<pubDate>Sun, 09 Aug 2009 04:44:03 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Breaking News]]></category>
		<category><![CDATA[Living with SCD]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=220</guid>
		<description><![CDATA[Alicia Bibbs, an SCCF founder &#38; research student, is pictured with her brother Dominick who suffers from sickle cell disease and recently recovered from surgery to have his spleen and gall bladder removed.]]></description>
			<content:encoded><![CDATA[<div id="attachment_221" class="wp-caption alignleft" style="width: 235px"><img class="size-full wp-image-221" title="aliciaanddominickbibbs" src="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/aliciaanddominickbibbs.jpg" alt="Alicia &amp; Dominick Bibbs" width="225" height="172" /><p class="wp-caption-text">Alicia &amp; Dominick Bibbs</p></div>
<p>Alicia Bibbs, an SCCF founder &amp; research student, is pictured with her brother Dominick who suffers from sickle cell disease and recently recovered from surgery to have his spleen and gall bladder removed.</p>
]]></content:encoded>
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		<slash:comments>7</slash:comments>
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		<item>
		<title>Radio Interview with Dr. Broyles</title>
		<link>http://sicklecellcurefoundation.org/2009/08/radio-interview-with-dr-broyles/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/radio-interview-with-dr-broyles/#comments</comments>
		<pubDate>Sun, 09 Aug 2009 00:37:10 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Breaking News]]></category>
		<category><![CDATA[sickle cell cure foundation]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>
		<category><![CDATA[sickle cell disease cure]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=159</guid>
		<description><![CDATA[Dr. Broyles was interviewed by radio station KTOK on Easter Sunday April 12, 2009. To listen to the audio, click on the play button.http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/Dr._Robert_Broyles.mp3]]></description>
			<content:encoded><![CDATA[<div style="float: left; width: 227px; height: 275px;"><img title="Dr. Broyles" src="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2010/01/robert1.jpg" alt="Dr. Broyles" width="250" height="250" /></div>
<div style="float: right; width: 315px;">
<p>Dr. Broyles was interviewed by radio station KTOK on Easter Sunday April 12, 2009.  To listen to the audio, click on the play button.<!-- Dewplayer Begin--><object type="application/x-shockwave-flash" data="http://sicklecellcurefoundation.org/wp-content/plugins/dewplayer-flash-mp3-player/dewplayer.swf?mp3=http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/Dr._Robert_Broyles.mp3&amp;bgcolor=FFFFFF" width="200" height="20"><param name="bgcolor" value="FFFFFF" /><param name="movie" value="http://sicklecellcurefoundation.org/wp-content/plugins/dewplayer-flash-mp3-player/dewplayer.swf?mp3=http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/Dr._Robert_Broyles.mp3&amp;bgcolor=FFFFFF" /></object><!-- Dewplayer End--><a href="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/Dr._Robert_Broyles.mp3">http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/08/Dr._Robert_Broyles.mp3</a></p>
</div>
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		<slash:comments>18</slash:comments>
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		<title>World Sickle Cell Day</title>
		<link>http://sicklecellcurefoundation.org/2009/08/137/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/137/#comments</comments>
		<pubDate>Sat, 08 Aug 2009 21:03:18 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Breaking News]]></category>
		<category><![CDATA[united states patent]]></category>
		<category><![CDATA[world sickle cell day]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/2009/08/137/</guid>
		<description><![CDATA[In celebration of World Sickle Cell Day , the SCCF announces its GLOBAL Request for Proposals to Partner (RFPP), attached as a PDF. RFPP-19-JUN-09[rev].pdf Abstract &#8211; United States Patent # 7,517,669 Issued April 14, 2009 A method is described for regulating gene expression related to iron metabolism to ameliorate diseases that include sickle cell, cancers, [...]]]></description>
			<content:encoded><![CDATA[<p><img alt="" src="/wp-content/uploads/2009/08/people-globe-full.jpg" title="people-globe-full" class="aligncenter" width="586" height="284" /></p>
<div style="margin: 0pt 15px 0pt 0pt; float: left; width: 47%;">
<p>In celebration of World Sickle Cell Day , the SCCF announces its GLOBAL Request for Proposals to Partner (RFPP), attached as a PDF. <a href="/wp-content/plugins/downloads-manager/upload/RFPP-19-JUN-09[rev].pdf">RFPP-19-JUN-09[rev].pdf</a></p>
<h3>Abstract &#8211; United States Patent  # 7,517,669 Issued April 14, 2009</h3>
<p>A method is described for regulating gene expression related to iron metabolism to ameliorate diseases that include sickle cell, cancers, neurodegenerative diseases, Friedriech’s ataxia, and other neuromuscular disorders, and atherosclerosis.  This approach is illustrated by recent findings that show that ferritin-H, an iron-binding protein that is present in cell nuclei can repress the human β- globin gene, the gene that is mutated in sickle cell disease. <span style="color: #0000ff;"> Increased expression of ferritin-H</span> or a related ferritin-family peptide, <span style="color: #0000ff;">given to mutated cells</span> either as the peptide itself (or a part thereof), as an expression clone of the ferritin-H-subfamily gene, ou via a gene regulator that increases expression of the ferrritin-H-subfamily gene itself, <span style="color: #0000ff;">prevents or ameliorates expression of the disease state in disorders where increased availability of iron is implicated</span> in the etiology of the disease, including those named above.</p>
<p>[Text in blue presents the essential argument and finding.]</p></div>
<div style="margin: 0pt; float: left; width: 47%;">
<p>A PDF of a talk presented 11 June 2009 in Porto, Portugal, to representatives from 30 countries attending the International BioIron Society World Congress. <a href="/wp-content/plugins/downloads-manager/upload/IBIS-GeneRegulTherapy(abbrev.).pdf">IBIS-GeneRegulTherapy(abbrev.).pdf</a></p>
<h3>Sommaire du Brevet No. 7,517,669 des Etats-Unis Emis le 14 avril 2009</h3>
<p>Une thérapie est décrite pour régler l’expression génétique afférant  au métabolisme de fer afin d’améliorer les symptômes  des victimes de certaines maladies telles que la drépanocytose, des cancers, des maladies neurodégénératives, l’ataxia de Friedreich, autres désordres neuromusculaires, et l’athérosclerosis.  Des découvertes récentes illustrent que cette thérapie à base de la ferritine-H, une protéine qui fixe le fer et qui se trouve dans les nuclei des cellules, peut  réprimer  le gène humain β-globine, le gène qui porte la mutation drépanocytaire. <span style="color: #0000ff;"> L’expression accrue de la ferritine-H</span> ou d’une peptide liée à la famille des ferritines, <span style="color: #0000ff;">donnée aux cellules mutées</span> &#8212; soit sous forme d’une peptide (ou d’une partie en conséquence), soit comme une expression clône du gène de la sous-famille ferritine-H, soit par voie d’un gène régulateur qui fait accroître l’expression du gène de la ferritine-H lui-même <span style="color: #0000ff;">empêche l’expression ou améliore les symptômes des maladies dans les cas où une disponibilité accrue du fer est impliquée</span> dans leur étiologie y compris les désordres cités en haut.</p>
<p>[Le texte en bleu présente l’essentiel de l’argument et la découverte.]</p></div>
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		<title>Clinical Trials</title>
		<link>http://sicklecellcurefoundation.org/2009/08/press-release/</link>
		<comments>http://sicklecellcurefoundation.org/2009/08/press-release/#comments</comments>
		<pubDate>Fri, 07 Aug 2009 17:31:35 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Breaking News]]></category>
		<category><![CDATA[clinical trials]]></category>
		<category><![CDATA[funding]]></category>
		<category><![CDATA[Patent]]></category>
		<category><![CDATA[sickle cell cure foundation]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>
		<category><![CDATA[sickle cell disease cure]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=469</guid>
		<description><![CDATA[PRESS RELEASE No. 01 DATE: APRIL 2, 2009 CONTACT: ROBERT H. BROYLES, PhD E-MAIL: TELEPHONE : 001-405-922-5774 CURE FOR SICKLE CELL DISEASE PATENTED! U.S. RESEARCH FOUNDATION TO BEGIN CLINICAL TRIALS Scientists around the globe know that a newborn’s production of fetal red blood cells (HbF) declines soon after birth and transitions to the production of [...]]]></description>
			<content:encoded><![CDATA[<p><img alt="" src="/wp-content/uploads/2009/08/african-outstreched-hands-full.jpg" title="/wp-content/uploads/2009/08/african-outstreched-hands-full.jpg" class="aligncenter" width="586" height="293" /></p>
<div style="margin: 0pt 15px 0pt 0pt; float: left; width: 47%;">
<h3>PRESS RELEASE</h3>
<p>No. 01<br />
DATE: APRIL 2, 2009</p>
<p>CONTACT: ROBERT H. BROYLES, PhD<br />
E-MAIL: <script type="text/javascript"> // <!-- 
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// --> </script><span class="email_text">robert &laquo;dot&raquo; broyles &laquo;at&raquo; sicklecellcurefoundation &laquo;dot&raquo; org</span><script type="text/javascript"> // <!-- 
jQuery(".email_text").each(function() { this.innerHTML = "" } )
 // --> </script><br />
TELEPHONE : 001-405-922-5774</p>
<h3><strong>CURE FOR SICKLE CELL DISEASE PATENTED!</strong></h3>
<p><strong>U.S. RESEARCH FOUNDATION TO BEGIN CLINICAL TRIALS</strong></p>
<p>Scientists around the globe know that a newborn’s production of fetal red blood cells (HbF) declines soon after birth and transitions to the production of adult red blood cells.  Medical researchers have also shown that HbF alleviates the symptoms of sickle cell disease.<br />
Two years ago Dr. Robert H. Broyles demonstrated under controlled laboratory conditions that gene regulation therapy can re-start the body’s production of HbF- even in adults.  This discovery could lead to the elimination of the terrible symptoms of this deadly disease inherited by over a thousand children each day.<br />
After establishing the Sickle Cell Cure Foundation, Inc. (SCCF), a non-profit medical research firm, Dr. Broyles is eager to begin clinical trials of the cure that is expected to be more effective and cost far less than standard sickle cell treatments.  Twelve countries have already granted patent protection for this break-through discovery.  Also, SCCF’s legal counsel recently received a Notice of Allowance from the U.S. Patent Office validating the new cure.<br />
Soon SCCF intends to issue a worldwide request for proposals, aimed especially at non-profits, that would like to partner with SCCF in its conduct of clinical trials.  Qualified entities are asked to e-mail their expressions of interest no later than April 12, 2009.</p></div>
<div style="margin: 0pt; float: left; width: 47%;">
<h3>COMMUNIQUE DE PRESSE</h3>
<p>No. 1<br />
DATE: le 2 avril 2009</p>
<p>CONTACT: Docteur Robert BROYLES<br />
Message électronique: <script type="text/javascript"> // <!-- 
eval(unescape('%64%6f%63%75%6d%65%6e%74%2e%77%72%69%74%65%28%27%3c%61%20%68%72%65%66%3d%22%6d%61%69%6c%74%6f%3a%72%6f%62%65%72%74%2e%62%72%6f%79%6c%65%73%40%73%69%63%6b%6c%65%63%65%6c%6c%63%75%72%65%66%6f%75%6e%64%61%74%69%6f%6e%2e%6f%72%67%22%3e%72%6f%62%65%72%74%20%64%6f%74%20%62%72%6f%79%6c%65%73%20%61%74%20%73%69%63%6b%6c%65%63%65%6c%6c%63%75%72%65%66%6f%75%6e%64%61%74%69%6f%6e%20%64%6f%74%20%6f%72%67%3c%2f%61%3e%27%29'))
// --> </script><span class="email_text">robert &lt;dot&gt; broyles &lt;at&gt; sicklecellcurefoundation &lt;dot&gt; org</span><script type="text/javascript"> // <!-- 
jQuery(".email_text").each(function() { this.innerHTML = "" } )
 // --> </script><br />
TELEPHONE : 001-405-922-5774</p>
<h3><strong>BREVET POUR UNE GUÉRISON CONTRE LA DRÉPANOCYTOSE !</strong></h3>
<p><strong>FONDATION AMÉRICAINE PRÊTE À LANCER DES ESSAIS CLINIQUES</strong></p>
<p>Partout dans le monde les chercheurs savent  que la production des globules     rouges fœtales (HbF) commence à se réduire bientôt après la naissance du     nouveau-né en faveur des globules adultes.  Egalement les savants en médecine     ont démontré maintes fois que les globules rouges infantiles éliminent les     symptômes de la drépanocytose.<br />
Il y deux ans le docteur Robert Broyles a démontré sous des conditions contrôlées de laboratoire qu’une nouvelle thérapie de régulation génétique peut commencer de nouveau la production de globules rouges fœtales HbF chez les adultes.  Cette découverte pourrait amener à la disparition des symptômes horribles de cette maladie mortelle qui touche plus de mille nouveaux victimes tous les  jours.<br />
Après avoir fondé la Sickle Cell Cure Foundation, Inc. (SCCF), une société de recherches médicales à but non-lucratif, le docteur Broyles est prêt à démarrer des essais cliniques de la guérison qu’il s’attend à être plus efficace et nettement moins chère que le traitement drépanocytaire d’aujourd’hui.  Douze pays lui ont déjà accordé des brevets pour protéger cette découverte importante.   D’Ailleurs, le conseiller légal de la fondation SCCF a récemment reçu une Notification de Permis de la part du bureau américain de brevets (U.S. Patent Office), une étape qui vérifie la validité de la recherche.<br />
Bientôt la SCCF souhaite émettre une demande globale de propositions de partenariat destinée en particulier aux non-lucratifs qui voudraient travailler auprès de la SCCF dans sa conduite des essais cliniques.  Tous les partis qualifiés sont priés d’exprimer leur intérêt par message électronique le 12 avril 2009 au plus tard.</p></div>
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		<title>Our Research</title>
		<link>http://sicklecellcurefoundation.org/2009/07/our-research/</link>
		<comments>http://sicklecellcurefoundation.org/2009/07/our-research/#comments</comments>
		<pubDate>Sat, 25 Jul 2009 00:42:14 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Our Research]]></category>
		<category><![CDATA[gene regulation therapy]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=64</guid>
		<description><![CDATA[We have named our approach to curing sickle cell disease Gene Regulation Therapy, and the result is called a phenotypic cure. That is to say, no genes are permanently altered; instead, we use normal bodily signals to turn off the sickle cell gene and activate another gene with the same function in its place. We [...]]]></description>
			<content:encoded><![CDATA[<div id="attachment_249" class="wp-caption alignleft" style="width: 202px"><img class="size-full wp-image-249" title="grt" src="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/07/grt1.png" alt="Gene Regulation Therapy" width="192" height="250" /><p class="wp-caption-text">Gene Regulation Therapy</p></div>
<p>We have named our approach to curing sickle cell disease Gene Regulation Therapy, and the result is called a phenotypic cure. That is to say, no genes are permanently altered; instead, we use normal bodily signals to turn off the sickle cell gene and activate another gene with the same function in its place. We have discovered a naturally occurring protein, a protein that is grown in our bodies that will shut off the sickle cell gene. This same protein will also turn on a fetal hemoglobin gene to replace the silenced sickle hemoglobin. There are a few people in the world in which this substitution of fetal hemoglobin for sickle hemoglobin occurs naturally, and these people never have the devastating effects of sickle cell disease or any other physical problems. Our recent experiments with blood from sickle cell patients have shown that this approach will work as predicted. The treatment should be easy to deliver, as a protein directly into the blood or marrow, where red cell precursors have receptors on their surface that recognize this protein and internalize it. We have also discovered a plant compound that will activate expression of this protein in human cells, and the plant compound will be tested for both safety and effectiveness in humans with sickle cell or beta-thalassemia.</p>
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		<title>J.R. Perry III and his son Jameel</title>
		<link>http://sicklecellcurefoundation.org/2009/07/j-r-perry-iii-and-his-son-jameel/</link>
		<comments>http://sicklecellcurefoundation.org/2009/07/j-r-perry-iii-and-his-son-jameel/#comments</comments>
		<pubDate>Sat, 25 Jul 2009 00:39:21 +0000</pubDate>
		<dc:creator>broylesr</dc:creator>
				<category><![CDATA[Living with SCD]]></category>
		<category><![CDATA[j.r. perry III]]></category>
		<category><![CDATA[Sickle Cell Disease]]></category>

		<guid isPermaLink="false">http://sicklecellcurefoundation.ecoonamoly.com/?p=61</guid>
		<description><![CDATA[Jameel was born in 1999, and within 2 hours of his birth his father J.R. knew that his son would suffer from sickle cell disease. J.R. has devoted the rest of his life to raising awareness of SCD and the need for a cure. A musician, song-writer, promoter, and talk show host, J.R. Perry has [...]]]></description>
			<content:encoded><![CDATA[<div id="attachment_216" class="wp-caption alignleft" style="width: 145px"><img class="size-full wp-image-216" title="jrperry" src="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/07/jrperry.jpg" alt="JR Perry" width="135" height="158" /><p class="wp-caption-text">JR Perry</p></div>
<div id="attachment_217" class="wp-caption alignright" style="width: 285px"><img class="size-full wp-image-217" title="jameelkeyboard" src="http://sicklecellcurefoundation.ecoonamoly.com/wp-content/uploads/2009/07/jameelkeyboard.bmp" alt="jameelkeyboard" width="275" height="205" /><p class="wp-caption-text">Jameel on the keyboard</p></div>
<p>Jameel was born in 1999, and within 2 hours of his birth his father J.R. knew that his son would suffer from sickle cell disease. J.R. has devoted the rest of his life to raising awareness of SCD and the need for a cure. A musician, song-writer, promoter, and talk show host, J.R. Perry has planned a nation-wide music tour for 23 cities to raise money for a cure. J.R.’s effort is called “Cure Every Cell” and forms a perfect complement to the Sickle Cell Cure Foundation’s goals.</p>
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		<slash:comments>16</slash:comments>
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